M. Indriati Hood-Pishchany, MD, PhD
I am a Clinical Fellow in Pediatric Infectious Diseases studying microbial ecology of the female reproductive tract in the laboratory of Dr. Seth Rakoff-Nahoum at Boston Children’s Hospital.

The vaginal microbiome is emerging as central to reproductive tract health, impacting the risk of infection, preterm birth, and HIV acquisition. Despite this importance, we know relatively little about the ecological drivers that shape the female reproductive microbiome. One of the major barriers to further progress in this area is the lack of in depth phenotypic knowledge of the diverse bacterial species present within the reproductive tract, much less their potential for specific interactions. My work aims to address this gap by 1) phenotypic, genetic and molecular characterization of a broad collection of reproductive tract isolates representing the major constituents of the vaginal microbiome; 2) developing a robust in vitro culture system to model complex, polymicrobial communities, and 3) applying  “multiomics” approaches to measure both in vitro and in vivo interactions in the reproductive tract ecosystem.